RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-30e
RNA ID
MI0000259
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; dual-luciferase reporter assay etc.
Target
SNAIL
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
28777253
Title
MiR-30e attenuates isoproterenol-induced cardiac fibrosis through suppressing Snai1/TGFB signaling
Year
2017
Function
miR-30e suppressed Snai1/TGF-beta pathway which was involved in isoproterenol (ISO)-induced cardiac remodeling.